The medical black technology system of the top student

Early in the morning, Lu Liang yawned and got up from the bed with panda eyes.

After tinkering with the in vitro antibacterial activity test of three generations of evil spirits yesterday, he sorted out the data overnight and made an electronic experimental report.

On the one hand, this report is convenient for showing to Ji Hong.

On the other hand, the Drug Research Institute also needs to submit experimental reports regularly, and Lu Liang plans to submit this report when the time comes.

After briefly washing up and getting dressed, Lu Liang walked slowly into the cafeteria.

Steamed buns, glutinous rice chicken, fried noodles.

Lu Liang passed through these breakfast windows and finally stopped in front of a noodle window.

Bring me some fungus and shredded pork vermicelli.

Compared to breakfast of buns, steamed buns and corn on the cob, Lu Liang prefers to have a bowl of noodles when he wakes up in the morning.

In this way, even if you don't eat at noon, you won't feel too hungry.

If you just eat buns, steamed buns, etc., you will feel hungry in the afternoon.

After eating breakfast, Lu Liang walked towards the teaching building.

Arriving at the door of the office, the door was ajar. Lu Liang reached out and knocked on the door. Ji Hong's voice came from the room.

Please come in.

Lu Liang opened the door and walked in, finding Ji Hong talking on the phone.

Lu Liang didn't speak, but waited quietly.

When will this exchange meeting be held?

Yeah, okay, I'll see if I can arrange the itinerary then.

After Ji Hong hung up the phone, Lu Liang asked curiously: Teacher, is this an academic exchange meeting?

Ji Hong smiled and said, Well, it's an exchange meeting. The organizer invited us, but I can't seem to make time.

Lu Liang nodded suddenly.

Ji Hong suddenly remembered something. He looked at Lu Liang and began to consider it.

It has been almost two years since Lu Liang joined his team, but he has never attended an exchange meeting.

This might be a good opportunity.

After making the decision, Ji Hong said, Xiao Lu, how about this? How about you attend this academic exchange meeting instead of me?

Faced with the task that suddenly fell on him, Lu Liang was stunned.

Although he had participated in similar academic exchange meetings before, he had always attended them with his tutor.

But at those academic exchange meetings, the tutors and fellow PhD students are really responsible for communication. His main task is to go there and eat and drink.

Then after the exchange meeting, we took a short trip to the surrounding cities.

But under the current situation, Ji Hong obviously wanted him to attend the academic exchange meeting alone.

Lu Liangke had never had such an experience.

I don't have much experience in this area? Lu Liang was also hesitant.

It's okay, just relax. This kind of thing is just a simple exchange with other scholars, and everyone can discuss it among themselves.

Ji Hong paused and then said: If it doesn't work, Xiao Lu, just go out for a trip.

After all, we can't let you stay in the laboratory all day. It's time to go out for a walk, and the money for transportation and accommodation can be reimbursed.

Hearing Ji Hongdu speak like this, Lu Liang did not refuse: Then when will this academic exchange meeting start?

Ji Hong thought for a moment and said, It will probably take a while. There's no rush now. I'll let you know when the time is up.

After finalizing the academic exchange meeting, things got back to business again.

By the way, Xiao Lu, are you busy? Ji Hong asked.

Lu Liang also remembered the purpose of coming to Ji Hong this time: Teacher, there is something I want to report to you.

Ji Hong raised his eyebrows. Has he found any new research direction?

Otherwise, he couldn't think of any other reason why Lu Liang came to see him.

However, Ji Hong said: Xiao Lu, I'm just going to tell you something.

Lu Liang listened quietly.

Ji Hong said: In the future, if you have any new ideas or ideas that you think are feasible, you don't need to report them to me. You can try to do it yourself first.

In Ji Hong's view, Lu Liang is now fully capable of finding new directions independently.

There is no need to report to him anymore. It would be too troublesome to wait until he gets his consent before doing the experiment.

Moreover, there is not much he can give Lu Liang guidance now.

The only thing that might be able to help Lu Liang is to help Lu Liang analyze and find the reasons for the failure after some of Lu Liang's experiments failed.

After listening to Ji Hong's words, Lu Liang thought for a moment and then replied: I understand, teacher.

Ji Hong also nodded: Then just do it yourself. Just tell me what the final test results are.

But, teacher, I came here this time to report the test results to you?

Um?

Ji Hong suddenly showed a look of astonishment: No, Xiao Lu, when did you start the experiment again?

Lu Liang thought for a moment and replied: It was opened in the past two weeks.

Why don't I know?

I was so busy that I forgot to tell the teacher.

Lu Liang scratched his head and looked a little embarrassed: Besides, teacher, didn't you just say that I don't need to report to you, just tell you the results.

Ji Hong's expression suddenly became weird.

Well, that's exactly what he said, and he just said it.

Ji Hong coughed dryly: Well, that's good. Let's do this in the future. By the way, Xiaolu, please send me the results of your test.

Lu Liang quickly sent the experimental report he had prepared to Ji Hong.

Ji Hong asked: Xiao Lu, what kind of experiment are you doing this time?

Lu Liang replied: What we are doing this time is antibiotic-related research.

Antibiotics?

Ji Hong nodded thoughtfully. After receiving Lu Liang's experimental report, Ji Hong opened the report on his computer and glanced at Lu Liang's data.

Control group MIC90=2 ug/mL.

Test group MIC90=0.5 ug/mL

The antibacterial activity in vitro is 4 times stronger.

The sequencing results also did not detect the optrA gene.

Ji Hong nodded and commented: Judging from the data, the effect of your antibiotic is quite good.

But when he said this, Ji Hong paused for a moment: However, there is already a lot of research on antibiotics. If it is just ordinary antibiotics and you want to publish a paper, I'm afraid I won't be able to publish it in any good journals.

Ji Hong didn't mean to belittle Lu Liang. His evaluation was a very fair one.

Because from the medical field, the demand for ordinary antibiotics is not very big. After all, there are many types of antibiotics now, and ordinary antibiotics do not have much effect on those super bacteria.

What is really lacking are top-notch antibiotics that can fight superbugs.

Therefore, in Ji Hong's view, Lu Liang's research was a bit tasteless, and it felt like it was a waste of food and a pity to throw away.

But no matter what, this is the result of his students after all, and Ji Hong still wants to publish this research in a better journal as much as possible.

However, at this moment, Lu Liang coughed dryly: Teacher, you forgot to look at the bacteria used.

bacteria?

Could it make any difference?

Aren’t they basically Staphylococcus aureus and Pneumococcus?

Ji Hong rolled the mouse wheel in confusion and pulled up the report.

After seeing the bacteria used by Lu Liang in the experiment, Ji Hong was stunned.

Methicillin-resistant Staphylococcus aureus, multidrug-resistant Streptococcus pneumoniae, and vancomycin-resistant enterococci.

This is a superbug!

Especially when he saw vancomycin-resistant enterococci, Ji Hong's pupils shrank suddenly.

It can be said that in the field of antibiotics, vancomycin is a huge hurdle.

But when a certain type of bacteria becomes resistant to vancomycin, everyone should be vigilant.

Vancomycin-resistant enterococci are one of them. If Ji Hong remembers correctly, he remembers that the only antibiotic that is effective against vancomycin-resistant enterococci is now.

There are only first-generation oxazolidinone antibiotics, which are the antibiotics Lu Liang used in the control group.

And now, another brand-new antibiotic has emerged, which not only works against vancomycin enterococci, but is also four times more active than the first-generation oxazolidinone antibiotics!

Therefore, no matter how stupid Ji Hong is, he can still see the value of this antibiotic.

This is almost equivalent to establishing a new defense barrier between humans and bacteria!

After Ji Hong thought for a moment, he asked: Xiao Lu, does this antibiotic have any data on nephrotoxicity?

This hasn't been done yet. How about I wait a few days and conduct an animal test? Lu Liang said.

Ji Hong shook his head: No need, I will find someone to send it directly for testing, so that we can get the data in the shortest time and start the clinical trial.

Are you in such a hurry, teacher? Lu Liang asked in confusion.

Ji Hong did not answer, but asked Lu Liang: Xiao Lu, in your opinion, what is the disease that causes the most deaths in modern times?

Lu Liang thought for a moment: Cancer?

Nowadays, except for cancer, basically all kinds of diseases, big and small, have treatments, except cancer.

Nowadays, most cancers can only suppress the growth of cancer cells, but it is almost a difficult problem to cure them.

But Ji Hong shook his head: Xiao Lu, what I can tell you is that the number of deaths caused by bacterial infections is definitely no less than that caused by cancer.

Postoperative infections, respiratory infections, sepsis, some statistics show that among all deaths worldwide, bacterial infections account for 13.6%!

13.6%, this ratio may not seem high, but you must know that this is a statistic based on all death cases.

But if converted into numbers, the number of deaths caused by bacterial infections is as high as 7.7 million!

At the same time, deaths caused by bacterial infections have become the second leading cause of death in the world.

When he said this, Ji Hong paused: Every year, a large number of people die because of bacterial resistance, resulting in no available medicine.

Once this new antibiotic comes out, many problems will be solved.

Lu Liang nodded suddenly.

Okay, Xiao Lu, leave the drug and toxicology report and phase 3 clinical trial to me. I will be responsible for following up on the rest.

Ji Hong took this matter on himself.

Lu Liang nodded: Then it's up to you, teacher.